This work describes the development, optimization and validation of a reversed phase high-performance liquid chromatography (HPLC) method coupled with an ultraviolet visible detector (UV-VIS) by means of the conjugated ion pair technique (CIP), for the quantification of ascorbic acid, thiamine, riboflavin, nicotinamide, and pyridoxine in combined standard and loaded placebo. A LiChrospher® 100 RP-18 endcapped column (125 x 4.6 mm, 5 um) was used. UV detection was performed with a gradient of ...

The aim of this research work was to design a guide of Standard Operating Procedures (SOP ́s) for the application of Good Storage and Handling Practices (GSP) and distribution of medical devices, for the general warehouse belonging to the Alfonso Villagómez Román Paediatric Hospital of the Alfonso Villagómez Román Paediatric Hospital in the city of Riobamba. The research was carried out using tools such as observation, inventories, surveys and checklists, and was based on a diagnosis of the i...

In the present research work, the quality control of a milk collection center was carried out crude CA2., located in the province of Chimborazo canton Riobamba. Compliance was verified of the procedure’s manual issued by Agrocalidad, the physical-chemical analyzes were carried out in the Lactoscan MCCW equipment and for the microbiological analysis the counting technique was applied in plate on surface and in depth. The physical-chemical analysis shows a breach of the standard NTE INEN 9: 201...

This research work aimed to design protocols for the processes inherent to patient safety (pharmacovigilance and drug conciliation) at the Inginost Basic Hospital. The research was of a non-experimental field type, carried out under an observational and descriptive design, where it was necessary to delimit the population due to the inconveniences presented by the health personnel at the time of participation. The observational and descriptive technique made it possible to record information a...

The main objective of the research was to determine the degree of receptivity of health education campaigns on the rational use of antibiotics, through the biometric analysis applied to the population of the Polytechnic School of Chimborazo, which was conformed by six participants. For this, the Mindwave Neurosky neuronsignal capture device was used, which detected and recorded the brain responses of each of the users when observing the 3 videos of the campaigns, they were: the video proposed...

The main objective of the research work was to identify the alkaloids that are present in the Eucharis astrophiala bulb, for this, in the first place, the alkaloidal extract of the plant species was obtained using organic solvents and pH changes, once the vegetable sample went through the drying and crushing process. For the identification of the alkaloids, gas chromatography coupled to mass spectrometry was used, and once identified, the pharmacological potential of the alkaloids found was d...

The present research aimed to determine the prevalence of Metabolic Syndrome and its correlation with risk factors in employees and workers of the Ministry of Economic and Social Inclusion (MIES)- Guamote, in the period October 2020 - January 2021, through a descriptive non-experimental quantitative study. It was socialized with the staff of the MIES-Guamote inviting them to take a blood sample, executing a survey to assess their health status. A total of 100 blood serum samples were analysed...

The objective of this degree thesis is to determine the prevalence of the Metabolic Syndrome in the employees and workers of the Gobierno Autónomo Descentralizado Municipal del Cantón Colta. A quantitative, descriptive, and explanatory study was carried out in the Gobierno Autónomo Descentralizado Municipal the Colta in the period October 2020 to January 2021, with a population of 178 people who met the inclusion criteria, who were assessed: abdominal perimeter, weight, height, body mass inde...

Milling is a unit operation widely used in the food industry to turn grains, vegetables and meats into small-sized products. In this context. In this sense, a small-scale hammer mill was designed and built in order to reduce the size of dehydrated carrots and thus obtain a value-added food. Mill parameters such as force, torque and power were determined by theoretical calculations, while operational parameters such as milling coefficient and performance were determined by the carrot milling ...

The instrumentation of buildings allows us to evaluate and analyze the design of an existing building, and identify possible damage after the occurrence of a moderate to severe seismic event, considering the fundamental frequency as an essential parameter in the Dynamics of Structures. The purpose of this study is to analyze the fundamental frequencies of six structural models, and to compare the results obtained with the Modal Spectral and Step by step descriptive methods of analysis over ...

This study shows an analysis of the use of hemp as a potential alternative for the economic revival of Ecuador after the crisis experienced during and after the Covid-19 pandemic. To this end, three main points were studied: the economic approach, which shows the current situation of the Ecuadorian economy and the luxury of money generated by hemp worldwide, i.e. the main importers and exporters; the legal approach, which sets out the changes in Ecuadorian laws with respect to hemp and some ...

In this study, the capacity of isolated Chlorophyta algae from Limoncocha lagoon to remove organic matter in wastewater from the Shushufindi municipal slaughterhouse (Province of Sucumbios – Ecuador) was evaluated. Six different treatments of 1.8 L, with five replicates each, were applied in a tubular photobioreactor. The treatments aimed at assessing algae growth consisted of using of Nitrofoska foliar culture medium, with and without aeration; while for the organic matter reduction ...

In Morona Santiago province, 4%, 8% and 12% extract of Dulcamara Kalanchoe gastonis bonnieri was used in drinking water in broiler chickens of the COBB 500 line during the growth and fattening stage in order to reduce their morbidity and mortality compared to a control treatment to reduce production costs. The research design was experimental, quantitative, analytical. A random design with 4 treatments was applied to 100 one-day-old birds, each with 5 repetitions under controlled conditions; ...

Currently, in the area within higher education, data management has become essential for academic decision making and the improvement of educational processes. Analytics and statistics have been taken to the technological field, where the processes automation and the large databases management through Machine Learning algorithms are the most used, among which are the clustering algorithms, whose purpose is to group data by similarity. The objective of this study was to find types of universi...

Job stress involves a set of physiological, cognitive, emotional and behavioral reactions that the individual experiences when faced with circumstances that imply excessive pressure in a work context. This situation can have a negative impact on the performance, motivation, satisfaction and commitment of the worker with the company. Considering the complexity of the working conditions imposed by COVID-19 on health personnel, the objective of this study was to analyze work stress among prima...

The study and development of environmental laws that systematize the management of water bodies requires the identification of bioindicators to establish their ecological status. Therefore, this study aims to determine the macroinvertebrates diversity as bioindicators of Yuquipa river water quality. Three monitoring stations were studied on November, December 2020 and on January 2021; macroinvertebrates species were gathered and the Shannon index was used to measure species diversity, which e...

The construction of artificial wetlands for the water treatment from water bodies such as the “Rumiyacu” River, has the purpose of reducing organic and inorganic pollutants from lotic ecosystems through primary processes, such as sedimentation, enzymatic degradation, absorption and volatilization of compounds. For this, in this bioremediation process, plant species (grasses) of the area were used, such as: Echynochloa polystachya, Pennisetum purpureum, Panicum máximum, and Arvenses sp. T...

It is important that Ecuador carries out a diagnosis of its renewable energy potential; therefore, the following study was executed with data obtained from meteorological stations and with the help of software developed by the National Laboratory for Renewable Energy, Model System Advisor (SAM ), where high enthalpy systems with parabolic collectors were designed in various areas of the upper basin of the Pastaza River, based on its solar energy potential and available area, to generate elect...

This paper uses the concept of data depth as well as the nonparametric control chart developed by Regina Liu, to monitor student performance in a group of subjects at an educational institution over a given period of time. The methodology uses a reference set obtained from the results themselves rather than ideal standards. This reference set serves to calibrate the control chart and therefore monitor subsequent data. The concept of data depth allows creating a univariate index from, in t...