Elaboración y Determinación de Eficacia in Vivo de un Gel para el Acné a Base de Calaguala (Campyloneurum amphostenon).

Abstract

"The investigation project was carried out at the Escuela Superior Politécnica de Chimborazo at the Laboratories of the Science Faculty to claborate and determine the efficacy in vivo of a gel for the acne based on Calaguala (Campyloncurum amphostenon). For this extraction of active components of dry plant through percolation and its corresponding physical, chemical and microbiological quality control. The gel elaboration was performed wuith the extract and excipients which were subjected to quality control test. The chemical marker quantification was conducted through the spectrophotometric methods with positive results, as well as the physical evaluation of he efficacy in vivo in 40 voluntary people who were subjected to a rigorous treatment for cight weeks through weekly controls of grain counting and simple display together with the comparison against the commercial product OXY; therefore the quality control was carried out according to the Ecuatiran Norm for phytomedicines and the Pharmacopea Americana XXVIII. Therefore it is shown that there is a considerable improvement in people affected by such a disease and the decrease of grains produced by acne, which stresses it therapeutical efficacy, this is why it is recommended to carry out accelerated stability tests to lengthen the product service life."