Determinación del marcador tumoral CA 125 y su relación con factores de riesgo en estudiantes de Bioquímica y Farmacia - ESPOCH

Abstract

The main objective of this research study was to focus on ovarian cancer which is a malignant neoplasm that presents different histological types, among them the germ cell tumor that is recurrent in the young population. It was applied as a primary prevention measure, the determination of risk factors in complement with blood tests that include tumor markers, especially the carbohydrate antigen 125. This evaluation by enzyme-linked immune sorbent assay (ELISA) was applied to 90 students of Biochemistry and Pharmacy of the ESPOCH with prior authorization through informed consent and selection of the study sample based on the analysis of the survey carried out, for its subsequent statistical association with the results of the laboratory test thanks to the General Univariable Model. Using this methodology, the total study sample presented values below the cut-off point of ≤35 U/ml, i.e., the results were normal. Furthermore, it is established that the risk factors corresponding to age, pelvic pain, frequent urinary urination, pelvic inflammatory disease, obesity, and carbohydrate intake present a statistically significant effect on the tumor marker, consequently, complementary tests at both blood, genetic and imaging levels are recommended; as well as health promotion through health education in conjunction with timely treatment to prevent the onset of the disease.