Evaluación del efecto cicatrizante de extractos a base de mastuerzo (tropaeolum majus) en ratones (mus musculus).

Abstract

The healing effect of the extract hydro-alcoholic of Garden Cress (Tropaeolum majus) was evaluated at different concentrations in the Vivarium of Science Faculty of the Escuela Superior Politécnica de Chimborazo. Quality control of crude drug and the hydroalcoholic extract, were used for the evaluation of healing effect in injuries induced in mice (Mus musculus), considering the healing time and the scar final length, the results were analyzed statistically with an interval of 95% of confidence, by Anova and Tuckey tests. Through physico-chemical analysis of the extract hydro-alcoholic it could be determined that has a pH of 6.45; relative density 0,9652; refractive index 1,358 and 1.49% total solids. In the quantification of phenolic compounds it was obtained a value of 821,37 expressed as µg of Gallic acid/g of simple; total flavonoids were quantified, obtained a value of 30,89 expressed as µg of catechin/g of simple. This study concluded that, the hydroalcoholic extract of Garden Cress (Tropaeolum majus) resulted effective applied in injuries induced, with greater effect on concentration at 80% by presenting healing in 10 days, with a length of 1.4 cm scar. It is recommended to develop a pharmaceutical form to facilitate the administration of the extract of Garden Cress (Tropaeolum majus).