Desarrollo del Sistema de Farmacovigilancia en pacientes hospitalizados en el Área de Pediatría del Hospital IESS Riobamba.

Abstract

The objective was to evaluate, analyze the importance and benefits of the implementation of the Pharmacovigilance system (SF) in hospitalized patients in the Department of Pediatrics of Hospital IESS Riobamba. It determines the incidence of adverse drug reactions (ADRs) and the predisposing factors as a necessary activity to improve health care. This research used an observational study which included patients of both genders, to 15 years old. Each time a RAM was detected, we collected and analyzed all the data required, of which, level severity, incidence, causal link (using the Naranjo algorithm) and dose relationship were analyzed. From 61 hospitalized patients in the area of pediatrics, all met the study criteria and were included in the investigation. During research time 2 patients had some type of ADRs. This corresponds to 3.28%, whose drugs were involved in ADRs, the dexamethasone and metronidazole. ADRs identified were Rash Allergic and itching, and the most prevalent according to the dose relationship were type A and B with 50%. According to the severity level was moderate with 100% and according to the causality relationship was probable and possible with 50%. SF was developed by notifying the presence of ADRs in the service by using the yellow card, identifying Therapeutic profiles through research the reality of the population. It is recommended to continue the development of SF and rescue the importance of Pharmaceutical Biochemist.