Elaboración de una crema orgánica con actividad antiinflamatoria a base de productos naturales

Abstract

The aim of this work was to elaborate an organic cream with anti-inflammatory activity based on natural products, selecting Baccharis latifoliaknown as "chilca" in which its leaves were mainly used. It started by collecting the sample, the determination of the quality parameters of the plant, as well as the hydroalcoholic extract by means of organoleptic and physicochemical tests. The identification of the secondary metabolites was carried out through phytochemical screening. Organic and natural excipients were used for the formulation of the anti-inflammatory organic cream. After the quality tests, both organoleptic and physicochemical, the best formulation was selected, later, the microbiological control and the stability study were developed for 15 days. Regarding the results of the quality control of the plant species, they showed that the values of humidity, total ashes, water-soluble ashes and hydrochloric acid insoluble are within the ranges established by the Real Farmacopea Española, the hydroalcoholic extract demonstrated that has an acceptable pH at skin level, by means of qualitative tests, the presence of secondary metabolites such as: flavonoids and triterpenes was determined. Nine formulations were elaborated and after the respective quality control, formulation eight was selected, which meets the requirements according to the INEN 2867 Standard and the ARCSA. In the microbiological control, the absence of microorganisms was evidenced achieving an innocuous final product. In conclusion, an organic cream with anti-inflammatory and moisturizing properties, safe and free of pathogens was obtained, meeting the quality requirements for its application. Finally, it is recommended to compare the effectiveness of the organic anti-inflammatory cream with products found in the pharmaceutical market.