Evaluación de alteraciones de marcadores tumorales (CEA, CA19-9 y CA15-3) y los factores de riesgo correlacionados a patologías gastrointestinales en los estudiantes de Bioquímica y Farmacia - ESPOCH, 2019

Abstract

The majority of cancer cases that affect the general population without any distinction are of a chronic-degenerative nature, becoming a serious public health problem; that is why the research aims to evaluate the alterations in tumor markers (MT) and risk factors correlated to gastrointestinal pathologies in Biochemistry and Pharmacy students at ESPOCH. A nonexperimental, qualitative, correlational, descriptive and cross-sectional study was carried out. 90 students of the career participated in whom surveys were applied to identify risk factors and the serum was subsequently analyzed to determine alterations in the TM through the competitivesandwich ELISA method. Where 73% correspond to the female gender, 65% are in the age group 21 - 24 years and risk factors such as 30% H. pylori infection, 22% family history of gastrointestinal cancer, 70% consumption of NSAIDs with a frequency of 1 - 5 months, 10% daily consumption of meat, 67% sometimes perform physical activity, 64% social drinker and 27% do not smoke, but have occasionally smoked; In addition, 12 positive samples for CEA were observed. Therefore, risk factors should not go unnoticed, because young university students follow wrong habits patterns that put their health at risk; jointly, it was found that there is a significant relationship between the alcoholic risk factor and the alteration of MT CEA in the development of gastrointestinal pathologies in students. Consequently, training for university students is recommended in the importance of tumor markers for the screening of neoplasms and the control of predisposing risk factors, so that timely treatment can be accessed.