Diseño e implementación de un biosensor basado en un resonador de anillo para la medición de soluciones de glucosa a distintas concentraciones.

Abstract

This thesis aimed to design and implement a biosensor based on a ring resonator for the measurement of glucose solutions at different concentrations. The study involved investigating the key characteristics of biosensors and ring resonators, as well as exploring the main features of the Vector Network Analyzer (VNA). Due to its optimal properties, an RT/Duroid material was chosen for the biosensor implementation. Once the biosensor was implemented, glucose, sucrose, and salt solutions were prepared at various concentrations to assess the biosensor's functionality and sensitivity. The Vector Network Analyzer (VNA) was employed to measure the amplitude when different solutions were placed on the biosensor. The transmission coefficient S21 was used for data analysis, revealing amplitude variations corresponding to the concentrations applied to the biosensor. Subsequently, blood samples were tested and compared with glucose concentrations to observe similarities in amplitude variations between blood and glucose concentrations. Changes in the biosensor's behavior were observed by comparing different concentrations of glucose, salt, sucrose, and blood. Therefore, it can be concluded that the biosensor can detect changes in amplitudes corresponding to the applied concentrations, indicating its responsiveness to these concentrations.