Determinación y estandarización de valores de referencia de química sanguínea I (glucosa, colesterol total, HDL, IDL, triacilgliceridos, ácido úrico, urea creatinina, y proteínas totales) en base al rango de edades en pacientes de 0 a 19 años del Hospital Pediátrico “Alfonso Villagómez Román".

Abstract

The aim of this work was to determine and standardize the reference ranges of blood chemistry test I (glucose, total cholesterol, HDL cholesterol, LDL cholesterol, triacylglycerides, uric acid, creatine, urea, and total protein) for patients aged from 0 to 19 at the Alfonso Villagómez Román Children Hospital. The total population was 628 patients whose samples were studied according to each parameter stablished using Linear and Cromatest. Patients were classified into age groups: 1-3 days, 1 week, 2 weeks, 1 month, 2 months, 3-6 months, 6-24 months, 2-4 years, 4-6 years, 6-12 years, and 12-19 years. T-Student test results showed that that there was no difference between males and females. Tukey test was used to determine the following reference ranges: glucose of 40 - 73 mg/dl in newborns and the other parameters of 60 - 110 mg/dl, total cholesterol of 50 - 130 mg/dl in newborns, HDL cholesterol of 30 - 66 mg/dl, LDL cholesterol of 55 - 140 mg/dl, triglycerides of 30 - 150 mg/dl, urea of 11 - 36 mg/dl, uric acid of 2.6 - 7 mg/dl, creatine of 0.25 - 1.20 mg/dl, and total protein of 5.20 - 8.32 mg/dl. These values vary according to age. Lab tests showed differences between males and females. For example, creatine values varied according to muscle mass, and uric acid varied due to patients’ physical conditions.